Vildagliptin Conversion To Sitagliptin Discount


DPP-IV INHIBITORS | JOHNS HOPKINS DIABETES GUIDE
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Dec 3, 2018 INDICATIONS FDA Type 2 diabetes mellitus MECHANISM Inhibits dipeptidyl peptidase IV (DPP-IV) enzyme, which prolongs the action of the incretin hormones, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic … ...

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COMPARISON OF VILDAGLIPTIN AND SITAGLIPTIN IN PATIENTS WITH …
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Jun 12, 2015 FPG decreased by 0.47 ± 0.37 mmol/l with vildagliptin and increased by 0.16 ± 0.43 mmol/l with sitagliptin ( p = 0.185). Both treatments were well tolerated with … ...
Author Wolfgang Kothny, Valentina Lukashevich, James E. Foley, Marc S. Rendell, Anja Schweizer
DOI 10.1007/s00125-015-3655-z
Publish Year 2015
Publication Diabetologia. 2015; 58(9)

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COMPARISON OF VILDAGLIPTIN TWICE DAILY VS. SITAGLIPTIN ONCE …
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Author Masaya Sakamoto, Rimei Nishimura, Rimei Nishimura, Taiga Irako, Daisuke Tsujino, Kiyotaka Ando, Kazu...
Estimated Reading Time 9 mins
Publish Year 2012
Published Aug 6, 2012

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DAPAGLIFLOZIN IS EFFECTIVE AS ADD-ON THERAPY TO …
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Feb 11, 2014 Slightly greater numerical reductions in HbA 1c were observed in the sitagliptin monotherapy stratum than in the sitagliptin plus metformin stratum; this … ...

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CHOOSING A GLIPTIN - PMC - NATIONAL CENTER FOR …
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This review focuses on gliptins (sitagliptin, vildagliptin, saxagliptin, linagliptin, and alogliptin) discussing pharmacokinetics, pharmacodynamics, efficacy, and safety. … ...
Author Vishal Gupta, Sanjay Kalra
DOI 10.4103/2230-8210.85583
Publish Year 2011
Published Oct-Dec 2011

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EFFICACY AND SAFETY OF VILDAGLIPTIN, SITAGLIPTIN, AND …
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Oct 19, 2015 We aimed to evaluate the efficacy and safety of the three dipeptidyl peptidase 4 (DPP-4) inhibitors (vildagliptin, sitagliptin, and linagliptin) as add-on therapy in … ...

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A RANDOMIZED CONTROLLED TRIAL OF VILDAGLIPTIN VERSUS
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Conclusion: The glucose-lowering effects of these three dipeptidyl peptidase-4 (DPP-4) inhibitors (vildagliptin, alogliptin, and sitagliptin) were different, and the effects of … ...

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COMPARISON OF VILDAGLIPTIN AND SITAGLIPTIN IN PATIENTS WITH …
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We compared the safety and efficacy of vildagliptin and sitagliptin in patients with type 2 diabetes and severe renal impairment (RI). Methods: This study was a parallel-arm, … ...

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EFFICACY AND SHORT-TERM SIDE EFFECTS OF SITAGLIPTIN, …
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Mar 1, 2019 Three hundred patients had been randomly allocated to sitagliptin 100 mg, once daily; vildagliptin 50 mg, twice daily and saxagliptin 5 mg, once daily for 12 weeks. … ...

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COMPARATIVE EFFICACY OF VILDAGLIPTIN AND SITAGLIPTIN IN
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Combining matched trials, vildagliptin 50 mg twice daily was associated with significantly greater absolute HbA(1c) reduction by 0.28% compared with sitagliptin 50 mg once … ...

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DPP-4 INHIBITORS | PRESCRIBING INFORMATION | DIABETES - TYPE 2
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Infections — increased risk with saxagliptin, alogliptin, and vildagliptin. Hypersensitivity reactions (including anaphylaxis) have been reported with sitagliptin, saxagliptin, … ...

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SITAGLIPTIN VS VILDAGLIPTIN: COMPARING JANUVIA VS GALVUS - DIBESITY
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Oct 4, 2021 Both Sitagliptin and Vildagliptin work in a glucose-dependent mechanism and are less likely to cause significant hypoglycemia unless they are used in combination … ...

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FULL ARTICLE: CARDIOVASCULAR SAFETY AND EFFECTIVENESS OF VILDAGLIPTIN ...
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Mar 31, 2020 Reprints & Permissions. View PDF View EPUB. Objectives: The dipeptidyl peptidase-4 (DPP-4) inhibitor vildagliptin is indicated for type 2 diabetes mellitus … ...

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COMPARISON OF VILDAGLIPTIN AND SITAGLIPTIN IN PATIENTS WITH
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Jun 12, 2015 At their recommended doses for severe RI, vildagliptin (50 mg once daily) compared with sitagliptin (25 mg once daily) demonstrated similar efficacy and both … ...

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A RANDOMIZED CONTROLLED TRIAL OF VILDAGLIPTIN VERSUS ALOGLIPTIN ...
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May 22, 2017 At 12 weeks after switching from vildagliptin to high-dose sitagliptin (100 mg daily), HbA1c was increased to 8.3%, but it was significantly (P < 0.05) reduced to … ...

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A RANDOMIZED CONTROLLED TRIAL OF VILDAGLIPTIN VERSUS ALOGLIPTIN ...
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May 22, 2017 After 12 weeks, patients who failed to achieve the target HbA1c level of < 7.0% with vildagliptin or alogliptin treatment were switched to high-dose sitagliptin (100 … ...

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COMPARISON OF EMPAGLIFLOZIN AND SITAGLIPTIN THERAPY ON ... - PUBMED
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Sep 1, 2021 Hematocrit and hemoglobin levels significantly increased in the empagliflozin group but not in the sitagliptin group. The global MPR significantly improved after … ...

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VILDAGLIPTIN OR SITAGLIPTIN? A COMPARISON IN PATIENTS WITH TYPE 2 ...
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Aug 1, 2015 HbA1c was reduced by 0.54% in patients treated with vildagliptin and 0.56% in patients treated with sitagliptin. Similarly, there was no significant difference in FPG … ...

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EFFICACY AND SAFETY OF VILDAGLIPTIN, SITAGLIPTIN, AND LINAGLIPTIN AS ...
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Oct 19, 2015 At week 12, mean FPG levels in the vildagliptin (7.31 ± 1.50 mmol/L) and linagliptin (6.90 ± 1.55 mmol/L) groups were significantly lower than in the sitagliptin … ...

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ENZYMATIC SYNTHESIS OF SITAGLIPTIN INTERMEDIATE USING A NOVEL ω ...
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Jan 1, 2019 In another study, approximately 114 mM of the sitagliptin precursor (R)-3-amino-4-(2,4,5-triflurophenyl) butanoic acid was generated from 140 mM pro-ketone with … ...

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TESTING THE THERAPEUTIC EQUIVALENCE OF ALOGLIPTIN, LINAGLIPTIN ...
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May 3, 2014 In our first analysis (Fig. 1 a), our equivalence testings found an equivalent treatment effect for linagliptin, sitagliptin, and vildagliptin given as monotherapy when … ...

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TENELIGLIPTIN VERSUS SITAGLIPTIN IN KOREAN PATIENTS WITH TYPE 2 ...
FREE From pubmed.ncbi.nlm.nih.gov
12 PMID: 30362280 PMCID: PMC6587707 DOI: 10.1111/dom.13566 Aim: To assess the efficacy and safety of add-on therapy with the dipeptidyl peptidase-4 inhibitor teneligliptin … ...

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SYNTHESIS OF SITAGLIPTIN INTERMEDIATE BY A MULTI-ENZYMATIC …
FREE From ncbi.nlm.nih.gov
Oct 6, 2021 Sitagliptin is a well-reported example of a drug containing a β-amino acid moiety as a key component. Sitagliptin, an inhibitor of dipeptidyl peptidase-4, is used as … ...

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